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Reciprocal Regulation of miR-122 and c-Myc in Hepatocellular Cancer: Role of E2F1 and TFDP2
c-Myc is a well-known oncogene frequently upregulated in different malignancies, whereas liver specific miR-122, a bona fide tumor suppressor, is downregulated in hepatocellular cancer (HCC). Here, we explored the underlying mechanism of reciprocal regulation of these two genes. Real-time RT-PCR and...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2013
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4199239/ https://ncbi.nlm.nih.gov/pubmed/24038073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26712 |
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