Methylation of the PTPRO Gene in Human Hepatocellular Carcinoma and Identification of VCP as Its Substrate

We have previously reported that the gene encoding protein tyrosine phosphatase receptor type-O (PTPRO) is suppressed by promoter methylation in a rat model of hepatocellular carcinoma (HCC) and it functions as tumor suppressor in leukemia and lung cancer. Here, we explored the methylation and expre...

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Hauptverfasser: Hsu, Shu-hao, Motiwala, Tasneem, Roy, Satavisha, Claus, Rainer, Mustafa, Mufaddal, Plass, Christoph, Freitas, Michael A., Ghoshal, Kalpana, Jacob, Samson T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199230/
https://ncbi.nlm.nih.gov/pubmed/23533167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.24525
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