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Impaired Alveologenesis and Maintenance of Secretory Mammary Epithelial Cells in Jak2 Conditional Knockout Mice

Jak2 is a hormone-receptor-coupled kinase that mediates the tyrosine phosphorylation and activation of signal transducers and activators of transcription (Stat). The biological relevance of Jak2-Stat signaling in hormone-responsive adult tissues is difficult to investigate since Jak2 deficiency lead...

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Autors principals: Wagner, Kay-Uwe, Krempler, Andrea, Triplett, Aleata A., Qi, Yongyue, George, Nicholas M., Zhu, Jianqiong, Rui, Hallgeir
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC419899/
https://ncbi.nlm.nih.gov/pubmed/15169911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.12.5510-5520.2004
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