PI3P phosphatase activity is required for autophagosome maturation and autolysosome formation

Autophagosome formation is promoted by the PI3 kinase complex and negatively regulated by myotubularin phosphatases, indicating that regulation of local phosphatidylinositol 3-phosphate (PtdIns3P) levels is important for this early phase of autophagy. Here, we show that the Caenorhabditis elegans my...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Wu, Yanwei, Cheng, Shiya, Zhao, Hongyu, Zou, Wei, Yoshina, Sawako, Mitani, Shohei, Zhang, Hong, Wang, Xiaochen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BlackWell Publishing Ltd 2014
Onderwerpen:
Scientific Reports
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198041/
https://ncbi.nlm.nih.gov/pubmed/25124690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201438618
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items