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Loss of C. elegans GON-1, an ADAMTS9 Homolog, Decreases Secretion Resulting in Altered Lifespan and Dauer Formation

ADAMTS9 is a metalloprotease that cleaves components of the extracellular matrix and is also implicated in transport from the endoplasmic reticulum (ER) to the Golgi. It has been reported that an ADAMTS9 gene variant is associated with type 2 diabetes. The underlying pathology of type 2 diabetes is...

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書目詳細資料
發表在:PLoS One
Main Authors: Yoshina, Sawako, Mitani, Shohei
格式: Artigo
語言:Inglês
出版: Public Library of Science 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517882/
https://ncbi.nlm.nih.gov/pubmed/26218657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133966
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