Ano1, a Ca(2+)-activated Cl(−) channel, coordinates contractility in mouse intestine by Ca(2+) transient coordination between interstitial cells of Cajal

Interstitial cells of Cajal (ICC) are pacemaker cells that generate electrical activity to drive contractility in the gastrointestinal tract via ion channels. Ano1 (Tmem16a), a Ca(2+)-activated Cl(−) channel, is an ion channel expressed in ICC. Genetic deletion of Ano1 in mice resulted in loss of sl...

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Bibliografski detalji
Glavni autori: Singh, Raman Deep, Gibbons, Simon J, Saravanaperumal, Siva Arumugam, Du, Peng, Hennig, Grant W, Eisenman, Seth T, Mazzone, Amelia, Hayashi, Yujiro, Cao, Chike, Stoltz, Gary J, Ordog, Tamas, Rock, Jason R, Harfe, Brian D, Szurszewski, Joseph H, Farrugia, Gianrico
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2014
Teme:
Alimentary
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198014/
https://ncbi.nlm.nih.gov/pubmed/25063822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.277152
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