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Inhibition of Cell Proliferation by a Selective Inhibitor of the Ca(2+)-activated Cl(−) Channel, Ano1

BACKGROUND: Ion channels play important roles in regulation of cellular proliferation. Ano1 (TMEM16A) is a Ca(2+)-activated Cl(−) channel expressed in several tumors and cell types. In the muscle layers of the gastrointestinal tract Ano1 is selectively expressed in interstitial cells of Cajal (ICC)...

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Main Authors: Mazzone, Amelia, Eisenman, Seth T., Strege, Peter R., Yao, Zhen, Ordog, Tamas, Gibbons, Simon J., Farrugia, Gianrico
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479349/
https://ncbi.nlm.nih.gov/pubmed/22995309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.09.022
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