Direct repression of anoctamin 1 (ANO1) gene transcription by Gli proteins

The Ca(2+)-activated Cl(−) channel, anoctamin 1 (Ano1, also known as transmembrane protein 16A) contributes to intestinal pacemaking, fluid secretion, cellular excitability, and tissue development. The human ANO1 promoter contains binding sites for the glioma-associated oncogene (Gli) proteins. We i...

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Vydáno v:FASEB J
Hlavní autoři: Mazzone, Amelia, Gibbons, Simon J., Eisenman, Seth T., Strege, Peter R., Zheng, Tenghao, D’Amato, Mauro, Ordog, Tamas, Fernandez-Zapico, Martin E., Farrugia, Gianrico
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2019
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463924/
https://ncbi.nlm.nih.gov/pubmed/30802137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201802373R
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