A novel exon in the human Ca(2+)-activated Cl(−) channel Ano1 imparts greater sensitivity to intracellular Ca(2+)

Anoctamin 1 (Ano1; TMEM16A) is a Ca(2+)-activated Cl(−) channel (CACC) expressed in interstitial cells of Cajal. The mechanisms by which Ca(2+) regulates Ano1 are incompletely understood. In the gastrointestinal tract, Ano1 is required for normal slow wave activity and is involved in regulating cell...

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Detalhes bibliográficos
Publicado no:Am J Physiol Gastrointest Liver Physiol
Main Authors: Strege, Peter R., Bernard, Cheryl E., Mazzone, Amelia, Linden, David R., Beyder, Arthur, Gibbons, Simon J., Farrugia, Gianrico
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Neurogastroenterology and Motility
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628966/
https://ncbi.nlm.nih.gov/pubmed/26359375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00074.2015
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