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Ectopic TBX1 suppresses thymic epithelial cell differentiation and proliferation during thymus organogenesis

The thymus and parathyroid glands arise from a shared endodermal primordium in the third pharyngeal pouch (3rd pp). Thymus fate is specified in the ventral 3rd pp between E9.5 and E11, whereas parathyroid fate is specified in the dorsal domain. The molecular mechanisms that specify fate and regulate...

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Autores principales: Reeh, Kaitlin A. G., Cardenas, Kim T., Bain, Virginia E., Liu, Zhijie, Laurent, Micheline, Manley, Nancy R., Richie, Ellen R.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Company of Biologists 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197657/
https://ncbi.nlm.nih.gov/pubmed/25053428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.111641
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