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Ectopic TBX1 suppresses thymic epithelial cell differentiation and proliferation during thymus organogenesis

The thymus and parathyroid glands arise from a shared endodermal primordium in the third pharyngeal pouch (3rd pp). Thymus fate is specified in the ventral 3rd pp between E9.5 and E11, whereas parathyroid fate is specified in the dorsal domain. The molecular mechanisms that specify fate and regulate...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Reeh, Kaitlin A. G., Cardenas, Kim T., Bain, Virginia E., Liu, Zhijie, Laurent, Micheline, Manley, Nancy R., Richie, Ellen R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197657/
https://ncbi.nlm.nih.gov/pubmed/25053428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.111641
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