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Tissue-specific roles for sonic hedgehog signaling in establishing thymus and parathyroid organ fate
The thymus and parathyroids develop from third pharyngeal pouch (3rd pp) endoderm. Our previous studies show that Shh null mice have smaller, aparathyroid primordia in which thymus fate specification extends into the pharynx. SHH signaling is active in both dorsal pouch endoderm and neighboring neur...
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| Published in: | Development |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Company of Biologists Ltd
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5117149/ https://ncbi.nlm.nih.gov/pubmed/27633995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.141903 |
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