CBFB-MYH11 hypomethylation signature and PBX3 differential methylation revealed by targeted bisulfite sequencing in patients with acute myeloid leukemia

BACKGROUND: Studying DNA methylation changes in the context of structural rearrangements and point mutations as well as gene expression changes enables the identification of genes that are important for disease onset and progression in different subtypes of acute myeloid leukemia (AML) patients. The...

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Detalhes bibliográficos
Main Authors: Hájková, Hana, Fritz, Markus Hsi-Yang, Haškovec, Cedrik, Schwarz, Jiří, Šálek, Cyril, Marková, Jana, Krejčík, Zdeněk, Dostálová Merkerová, Michaela, Kostečka, Arnošt, Vostrý, Martin, Fuchs, Ota, Michalová, Kyra, Cetkovský, Petr, Beneš, Vladimír
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197269/
https://ncbi.nlm.nih.gov/pubmed/25266220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-014-0066-4
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