CBFB-MYH11 hypomethylation signature and PBX3 differential methylation revealed by targeted bisulfite sequencing in patients with acute myeloid leukemia

BACKGROUND: Studying DNA methylation changes in the context of structural rearrangements and point mutations as well as gene expression changes enables the identification of genes that are important for disease onset and progression in different subtypes of acute myeloid leukemia (AML) patients. The...

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Bibliografski detalji
Glavni autori: Hájková, Hana, Fritz, Markus Hsi-Yang, Haškovec, Cedrik, Schwarz, Jiří, Šálek, Cyril, Marková, Jana, Krejčík, Zdeněk, Dostálová Merkerová, Michaela, Kostečka, Arnošt, Vostrý, Martin, Fuchs, Ota, Michalová, Kyra, Cetkovský, Petr, Beneš, Vladimír
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Short Report
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197269/
https://ncbi.nlm.nih.gov/pubmed/25266220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-014-0066-4
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