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HIV CTL escape: at what cost?

Recent data have established the HIV-1 and SIV escape CTL through epitope mutation. However, three novel studies prove that such escape comes at a "cost" to overall viral fitness. Understanding how HIV-1/SIV escape CTL and the impact of the escape mutations has tremendous importance in dev...

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Hlavní autor: Smith, Stephen M
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC419725/
https://ncbi.nlm.nih.gov/pubmed/15169568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-1-8
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