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CTL Escape and Viral Fitness in HIV/SIV Infection

Cytotoxic T lymphocyte (CTL) responses exert a suppressive effect on HIV and simian immunodeficiency virus (SIV) replication. Under the CTL pressure, viral CTL escape mutations are frequently selected with viral fitness costs. Viruses with such CTL escape mutations often need additional viral genome...

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Detalhes bibliográficos
Main Authors: Seki, Sayuri, Matano, Tetsuro
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250645/
https://ncbi.nlm.nih.gov/pubmed/22319514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2011.00267
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