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CTL Escape and Viral Fitness in HIV/SIV Infection
Cytotoxic T lymphocyte (CTL) responses exert a suppressive effect on HIV and simian immunodeficiency virus (SIV) replication. Under the CTL pressure, viral CTL escape mutations are frequently selected with viral fitness costs. Viruses with such CTL escape mutations often need additional viral genome...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Research Foundation
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3250645/ https://ncbi.nlm.nih.gov/pubmed/22319514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2011.00267 |
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