TP53 Mutational Status Is a Potential Marker for Risk Stratification in Wilms Tumour with Diffuse Anaplasia

PURPOSE: The presence of diffuse anaplasia in Wilms tumours (DAWT) is associated with TP53 mutations and poor outcome. As patients receive intensified treatment, we sought to identify whether TP53 mutational status confers additional prognostic information. PATIENTS AND METHODS: We studied 40 patien...

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Hlavní autoři: Maschietto, Mariana, Williams, Richard D., Chagtai, Tasnim, Popov, Sergey D., Sebire, Neil J., Vujanic, Gordan, Perlman, Elizabeth, Anderson, James R., Grundy, Paul, Dome, Jeffrey S., Pritchard-Jones, Kathy
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196953/
https://ncbi.nlm.nih.gov/pubmed/25313908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109924
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