Subtype-specific FBXW7 mutation and MYCN copy number gain in Wilms tumour

PURPOSE: Wilms tumour (WT), the most common paediatric renal malignancy, is associated with mutations in a number of well-characterised genes, most notably WT1, CTNNB1, WTX and TP53. However, the majority of cases do not harbour mutations in these genes. We hypothesised that additional drivers of tu...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Williams, Richard D, Al-Saadi, Reem, Chagtai, Tasnim, Popov, Sergey, Messahel, Boo, Sebire, Neil, Gessler, Manfred, Wegert, Jenny, Graf, Norbert, Leuschner, Ivo, Hubank, Mike, Jones, Chris, Vujanic, Gordan, Pritchard-Jones, Kathy
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122447/
https://ncbi.nlm.nih.gov/pubmed/20332316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-2890
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