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A Dynamic View of Molecular Switch Behavior at Serotonin Receptors: Implications for Functional Selectivity
Functional selectivity is a property of G protein-coupled receptors that allows them to preferentially couple to particular signaling partners upon binding of biased agonists. Publication of the X-ray crystal structure of serotonergic 5-HT(1B) and 5-HT(2B) receptors in complex with ergotamine, a dru...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4196896/ https://ncbi.nlm.nih.gov/pubmed/25313636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109312 |
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