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Membrane cholesterol access into a G-protein-coupled receptor
Cholesterol is a key component of cell membranes with a proven modulatory role on the function and ligand-binding properties of G-protein-coupled receptors (GPCRs). Crystal structures of prototypical GPCRs such as the adenosine A(2A) receptor (A(2A)R) have confirmed that cholesterol finds stable bin...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5321766/ https://ncbi.nlm.nih.gov/pubmed/28220900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14505 |
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