Membrane omega-3 fatty acids modulate the oligomerisation kinetics of adenosine A(2A) and dopamine D(2) receptors

Membrane levels of docosahexaenoic acid (DHA), an essential omega-3 polyunsaturated fatty acid (ω-3 PUFA), are decreased in common neuropsychiatric disorders. DHA modulates key cell membrane properties like fluidity, thereby affecting the behaviour of transmembrane proteins like G protein-coupled re...

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Publicado en:Sci Rep
Main Authors: Guixà-González, Ramon, Javanainen, Matti, Gómez-Soler, Maricel, Cordobilla, Begoña, Domingo, Joan Carles, Sanz, Ferran, Pastor, Manuel, Ciruela, Francisco, Martinez-Seara, Hector, Selent, Jana
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726318/
https://ncbi.nlm.nih.gov/pubmed/26796668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19839
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