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Therapeutic antisense oligonucleotides against cancer: hurdling to the clinic
Under clinical development since the early 90's and with two successfully approved drugs (Fomivirsen and Mipomersen), oligonucleotide-based therapeutics has not yet delivered a clinical drug to the market in the cancer field. Whilst many pre-clinical data has been generated, a lack of understan...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4196572/ https://ncbi.nlm.nih.gov/pubmed/25353019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2014.00087 |
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