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In situ drug-receptor binding kinetics in single cells: a quantitative label-free study of anti-tumor drug resistance

Many drugs are effective in the early stage of treatment, but patients develop drug resistance after a certain period of treatment, causing failure of the therapy. An important example is Herceptin, a popular monoclonal antibody drug for breast cancer by specifically targeting human epidermal growth...

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Detalhes bibliográficos
Main Authors: Wang, Wei, Yin, Linliang, Gonzalez-Malerva, Laura, Wang, Shaopeng, Yu, Xiaobo, Eaton, Seron, Zhang, Shengtao, Chen, Hong-Yuan, LaBaer, Joshua, Tao, Nongjian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196117/
https://ncbi.nlm.nih.gov/pubmed/25312029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06609
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