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Label-free measuring and mapping of binding kinetics of membrane proteins in single living cells
Membrane proteins (MPs) mediate a variety of cellular responses to extracellular signals. While MPs are intensely studied for their values as disease biomarkers and therapeutic targets, in situ investigation of binding kinetics of MPs with their ligands has been a challenge. Traditional approaches i...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3660014/ https://ncbi.nlm.nih.gov/pubmed/23000999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.1434 |
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