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Label-Free Imaging of Histamine Mediated G Protein-Coupled Receptors Activation in Live Cells

[Image: see text] G protein-coupled receptors (GPCRs) are the largest protein family for cell signal transduction, and most of them are crucial drug targets. Conventional label-free assays lack the spatial information to address the heterogeneous response from single cells after GPCRs activation. He...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Lu, Jin, Yang, Yunze, Wang, Wei, Li, Jinghong, Tao, Nongjian, Wang, Shaopeng
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2016
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5144837/
https://ncbi.nlm.nih.gov/pubmed/27802015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.6b02677
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