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Label-Free Quantification of Small Molecule Binding to Membrane Proteins on Single Cells by Tracking Nanometer-Scale Cellular Membrane Deformation

Measuring molecular binding to membrane proteins is critical for understanding cellular functions, validating biomarkers and screening drugs. Despite the importance, developing such a capability has been a difficult challenge, especially for small molecule binding to membrane proteins in their nativ...

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Bibliografski detalji
Izdano u:ACS Nano
Glavni autori: Zhang, Fenni, Jing, Wenwen, Hunt, Ashley, Yu, Hui, Yang, Yunze, Wang, Shaopeng, Chen, Hong-Yuan, Tao, Nongjian
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5851003/
https://ncbi.nlm.nih.gov/pubmed/29397682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.8b00235
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