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Label-Free Quantification of Small Molecule Binding to Membrane Proteins on Single Cells by Tracking Nanometer-Scale Cellular Membrane Deformation
Measuring molecular binding to membrane proteins is critical for understanding cellular functions, validating biomarkers and screening drugs. Despite the importance, developing such a capability has been a difficult challenge, especially for small molecule binding to membrane proteins in their nativ...
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| Publicado no: | ACS Nano |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5851003/ https://ncbi.nlm.nih.gov/pubmed/29397682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.8b00235 |
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