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Label-Free Quantification of Small Molecule Binding to Membrane Proteins on Single Cells by Tracking Nanometer-Scale Cellular Membrane Deformation

Measuring molecular binding to membrane proteins is critical for understanding cellular functions, validating biomarkers and screening drugs. Despite the importance, developing such a capability has been a difficult challenge, especially for small molecule binding to membrane proteins in their nativ...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:ACS Nano
Egile Nagusiak: Zhang, Fenni, Jing, Wenwen, Hunt, Ashley, Yu, Hui, Yang, Yunze, Wang, Shaopeng, Chen, Hong-Yuan, Tao, Nongjian
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5851003/
https://ncbi.nlm.nih.gov/pubmed/29397682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.8b00235
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