Spatial and temporal evolution of distal 10q deletion, a prognostically unfavorable event in diffuse low-grade gliomas

BACKGROUND: The disease course of patients with diffuse low-grade glioma is notoriously unpredictable. Temporal and spatially distinct samples may provide insight into the evolution of clinically relevant copy number aberrations (CNAs). The purpose of this study is to identify CNAs that are indicati...

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Autori principali: van Thuijl, Hinke F, Scheinin, Ilari, Sie, Daoud, Alentorn, Agusti, van Essen, Hendrik F, Cordes, Martijn, Fleischeuer, Ruth, Gijtenbeek, Anja M, Beute, Guus, van den Brink, Wimar A, Meijer, Gerrit A, Havenith, Miek, Idbaih, Ahmed, Hoang-Xuan, Khê, Mokhtari, Karima, Verhaak, Roel GW, van der Valk, Paul, van de Wiel, Mark A, Heimans, Jan J, Aronica, Eleonora, Reijneveld, Jaap C, Wesseling, Pieter, Ylstra, Bauke
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4195855/
https://ncbi.nlm.nih.gov/pubmed/25245118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0471-6
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