IDH mutation status and role of WHO grade and mitotic index in overall survival in grade II–III diffuse gliomas

Diffuse gliomas are up till now graded based upon morphology. Recent findings indicate that isocitrate dehydrogenase (IDH) mutation status defines biologically distinct groups of tumors. The role of tumor grade and mitotic index in patient outcome has not been evaluated following stratification by I...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol
Main Authors: Olar, Adriana, Wani, Khalida M, Diefes, Kristin, Heathcock, Lindsey E., van Thuijl, Hinke F., Gilbert, Mark R., Armstrong, Terri S., Sulman, Erik P., Cahill, Daniel P., Vera-Bolanos, Elizabeth, Yuan, Ying, Reijneveld, Jaap C., Ylstra, Bauke, Wesseling, Pieter, Aldape, Kenneth D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369189/
https://ncbi.nlm.nih.gov/pubmed/25701198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-015-1398-z
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