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Spatial and temporal evolution of distal 10q deletion, a prognostically unfavorable event in diffuse low-grade gliomas

BACKGROUND: The disease course of patients with diffuse low-grade glioma is notoriously unpredictable. Temporal and spatially distinct samples may provide insight into the evolution of clinically relevant copy number aberrations (CNAs). The purpose of this study is to identify CNAs that are indicati...

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Detalhes bibliográficos
Main Authors: van Thuijl, Hinke F, Scheinin, Ilari, Sie, Daoud, Alentorn, Agusti, van Essen, Hendrik F, Cordes, Martijn, Fleischeuer, Ruth, Gijtenbeek, Anja M, Beute, Guus, van den Brink, Wimar A, Meijer, Gerrit A, Havenith, Miek, Idbaih, Ahmed, Hoang-Xuan, Khê, Mokhtari, Karima, Verhaak, Roel GW, van der Valk, Paul, van de Wiel, Mark A, Heimans, Jan J, Aronica, Eleonora, Reijneveld, Jaap C, Wesseling, Pieter, Ylstra, Bauke
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4195855/
https://ncbi.nlm.nih.gov/pubmed/25245118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0471-6
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