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Multiple mechanisms determine the order of APC/C substrate degradation in mitosis
The ubiquitin protein ligase anaphase-promoting complex or cyclosome (APC/C) controls mitosis by promoting ordered degradation of securin, cyclins, and other proteins. The mechanisms underlying the timing of APC/C substrate degradation are poorly understood. We explored these mechanisms using quanti...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4195823/ https://ncbi.nlm.nih.gov/pubmed/25287299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201402041 |
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