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Timing of APC/C substrate degradation is determined by fzy/fzr specificity of destruction boxes

The anaphase promoting complex/cyclosome (APC/C), activated by fzy and fzr, degrades cell cycle proteins that carry RXXL or KEN destruction boxes (d-boxes). APC/C substrates regulate sequential events and must be degraded in the correct order during mitosis and G(1). We studied how d-boxes determine...

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Detalhes bibliográficos
Main Authors: Zur, Amit, Brandeis, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC126191/
https://ncbi.nlm.nih.gov/pubmed/12198152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf452
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