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Interplay between base excision repair activity and toxicity of 3-methyladenine DNA glycosylases in an E. coli complementation system
DNA glycosylases carry out the first step of base excision repair by removing damaged bases from DNA. The N3-methyladenine (3MeA) DNA glycosylases specialize in alkylation repair and are either constitutively expressed or induced by exposure to alkylating agents. To study the functional and evolutio...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4195818/ https://ncbi.nlm.nih.gov/pubmed/24709477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2014.03.007 |
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