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Interplay between base excision repair activity and toxicity of 3-methyladenine DNA glycosylases in an E. coli complementation system

DNA glycosylases carry out the first step of base excision repair by removing damaged bases from DNA. The N3-methyladenine (3MeA) DNA glycosylases specialize in alkylation repair and are either constitutively expressed or induced by exposure to alkylating agents. To study the functional and evolutio...

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Detalhes bibliográficos
Main Authors: Troll, Christopher J., Adhikary, Suraj, Cueff, Marie, Mitra, Ileena, Eichman, Brandt F., Camps, Manel
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4195818/
https://ncbi.nlm.nih.gov/pubmed/24709477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2014.03.007
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