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DNA damage recognition and repair by 3-methyladenine DNA glycosylase I (TAG)

DNA glycosylases help maintain the genome by excising chemically modified bases from DNA. Escherichia coli 3-methyladenine DNA glycosylase I (TAG) specifically catalyzes the removal of the cytotoxic lesion 3-methyladenine (3mA). The molecular basis for the enzymatic recognition and removal of 3mA fr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Metz, Audrey H, Hollis, Thomas, Eichman, Brandt F
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1864966/
https://ncbi.nlm.nih.gov/pubmed/17410210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601649
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