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Unraveling a connection between DNA demethylation repair and cancer
In this issue of Molecular Cell, Dango and Mosammaparast et al. discover that the human oxidative demethylase ALKBH3 functions in complex with a DNA helicase to eliminate N3-methylcytosine lesions from ssDNA, and that specific cancer cell lines are dependent on this activity for proliferation.
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| Publicado no: | Mol Cell |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5025764/ https://ncbi.nlm.nih.gov/pubmed/22055180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.10.009 |
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