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Location, location, and location: compartmentalization of Hedgehog signaling at primary cilia
Primary cilia are solitary, microtubule-based organelles that serve as signaling hubs for the Hedgehog (Hh) pathway, which regulates embryonic development and adult tissue homeostasis. While protein localization studies have suggested that the dynamic trafficking of Hh components at cilia plays an i...
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| Główni autorzy: | , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Blackwell Publishing Ltd
2014
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4195781/ https://ncbi.nlm.nih.gov/pubmed/25037564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201489294 |
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