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Microtubule motors drive Hedgehog signaling in primary cilia
The mammalian Hedgehog (Hh) signaling pathway is required for development and for maintenance of adult stem cells, and overactivation of the pathway can cause tumorigenesis. All responses to Hh family ligands in mammals require the primary cilium, an ancient microtubule-based organelle that extends...
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| Publicado no: | Trends Cell Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5258846/ https://ncbi.nlm.nih.gov/pubmed/27765513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2016.09.010 |
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