Inhibitor of κB kinase is required to activate a subset of interferon γ-stimulated genes

IκB kinase (IKK), discovered as the major activator of NF-κB, plays additional roles in signaling. By using mouse embryo fibroblasts (MEFs) lacking both the α and β subunits of IKK, we find that these proteins are required for induction of a major subset of IFNγ-stimulated genes and that this requir...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Sizemore, Nywana, Agarwal, Anju, Das, Kingshuk, Lerner, Natalia, Sulak, Michael, Rani, Sandhya, Ransohoff, Richard, Shultz, David, Stark, George R.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2004
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC419545/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15148408/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0401593101
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