Inhibitor of κB kinase is required to activate a subset of interferon γ-stimulated genes

IκB kinase (IKK), discovered as the major activator of NF-κB, plays additional roles in signaling. By using mouse embryo fibroblasts (MEFs) lacking both the α and β subunits of IKK, we find that these proteins are required for induction of a major subset of IFNγ-stimulated genes and that this requir...

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Detalhes bibliográficos
Main Authors: Sizemore, Nywana, Agarwal, Anju, Das, Kingshuk, Lerner, Natalia, Sulak, Michael, Rani, Sandhya, Ransohoff, Richard, Shultz, David, Stark, George R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC419545/
https://ncbi.nlm.nih.gov/pubmed/15148408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401593101
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