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Inhibitor of κB kinase is required to activate a subset of interferon γ-stimulated genes
IκB kinase (IKK), discovered as the major activator of NF-κB, plays additional roles in signaling. By using mouse embryo fibroblasts (MEFs) lacking both the α and β subunits of IKK, we find that these proteins are required for induction of a major subset of IFNγ-stimulated genes and that this requir...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC419545/ https://ncbi.nlm.nih.gov/pubmed/15148408 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401593101 |
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