Inhibitor of κB kinase is required to activate a subset of interferon γ-stimulated genes
IκB kinase (IKK), discovered as the major activator of NF-κB, plays additional roles in signaling. By using mouse embryo fibroblasts (MEFs) lacking both the α and β subunits of IKK, we find that these proteins are required for induction of a major subset of IFNγ-stimulated genes and that this requir...
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| Опубликовано в:: | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC419545/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15148408/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0401593101 |
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