Early Alzheimer disease-like histopathology increases in frequency with age in mice transgenic for beta-APP751.
beta-Amyloid deposition and neurofibrillary tangle formation are two histopathological features of Alzheimer disease. We have previously reported that beta-amyloid immunoreactive deposits form in the brains of transgenic mice programmed for neuronal expression of the 751-amino acid isoform of human...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1995
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41952/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7753818/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.10.4402 |
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