Early Alzheimer disease-like histopathology increases in frequency with age in mice transgenic for beta-APP751.

beta-Amyloid deposition and neurofibrillary tangle formation are two histopathological features of Alzheimer disease. We have previously reported that beta-amyloid immunoreactive deposits form in the brains of transgenic mice programmed for neuronal expression of the 751-amino acid isoform of human...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Higgins, L S, Rodems, J M, Catalano, R, Quon, D, Cordell, B
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41952/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7753818/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.10.4402
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