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Expression of the adenovirus E4 34k oncoprotein inhibits repair of double strand breaks in the cellular genome of a 293-based inducible cell line

The human adenovirus E4 ORF 6 34 kDa oncoprotein (E4 34k), in concert with the 55 kDa product of E1b, prevents concatenation of viral genomes in infected cells, inhibits the repair of double strand breaks (DSBs) in the viral genome, and inhibits V(D)J recombination in a plasmid transfection assay. T...

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Detalhes bibliográficos
Main Authors: Mohammadi, Elham S., Ketner, Elizabeth A., Johns, David C., Ketner, Gary
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC419473/
https://ncbi.nlm.nih.gov/pubmed/15141036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh593
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