Intranasal vaccination with recombinant receptor-binding domain of MERS-CoV spike protein induces much stronger local mucosal immune responses than subcutaneous immunization: Implication for designing novel mucosal MERS vaccines

Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV) was originally identified in Saudi Arabia in 2012. It has caused MERS outbreaks with high mortality in the Middle East and Europe, raising a serious concern about its pandemic potential. Therefore, development of effective vaccines is cr...

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Main Authors: Ma, Cuiqing, Li, Ye, Wang, Lili, Zhao, Guangyu, Tao, Xinrong, Tseng, Chien-Te K., Zhou, Yusen, Du, Lanying, Jiang, Shibo
פורמט: Artigo
שפה:Inglês
יצא לאור: Elsevier Ltd. 2014
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Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4194189/
https://ncbi.nlm.nih.gov/pubmed/24560617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2014.02.004
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