Intranasal vaccination of recombinant H5N1 HA1 proteins fused with foldon and Fc induces strong mucosal immune responses with neutralizing activity: Implication for developing novel mucosal influenza vaccines

The highly pathogenic avian influenza (HPAI) H5N1 virus remains a threat to public health because of its continued spread in poultry in some countries and its ability to infect humans with high mortality rate, calling for the development of effective and safe vaccines against H5N1 infection. Here, w...

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Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: Yu, Fei, Li, Ye, Guo, Yan, Wang, Lili, Yang, Jie, Zhao, Guangyu, Zhou, Yusen, Du, Lanying, Jiang, Shibo
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5054784/
https://ncbi.nlm.nih.gov/pubmed/26260706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2015.1074363
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