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MicroRNA-125b induces tau hyperphosphorylation and cognitive deficits in Alzheimer's disease
Sporadic Alzheimer's disease (AD) is the most prevalent form of dementia, but no clear disease-initiating mechanism is known. Aβ deposits and neuronal tangles composed of hyperphosphorylated tau are characteristic for AD. Here, we analyze the contribution of microRNA-125b (miR-125b), which is e...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4194100/ https://ncbi.nlm.nih.gov/pubmed/25001178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201387576 |
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