The Molecular Basis for Ca(2+) Signalling by NAADP: Two-Pore Channels in a Complex?
NAADP is a potent Ca(2+) mobilizing messenger in a variety of cells but its molecular mechanism of action is incompletely understood. Accumulating evidence indicates that the poorly characterized two-pore channels (TPCs) in animals are NAADP sensitive Ca(2+)-permeable channels. TPCs localize to the...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4193953/ https://ncbi.nlm.nih.gov/pubmed/25309835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1166/msr.2012.1003 |
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